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However, when bacteria are exposed to excessive oxidative stress, which overwhelms their capacity to process ROS, they may undergo self-destruction ( A
De Feo CJ, Aller SG, Siluvai GS, Blackburn NJ, Unger VM
Chin Med
The crystal structure of human GPx3 revealed that each subunit contained a selenocysteine (Sec) residue and the active Sec-53 was located in a pocket on the protein surface with Gln-87, Trp-161 and Asn-162 nearby 13 , which formed a catalytic tetrad highly conserved in the selenium-dependent GPx family 14
However, more research is needed to fully understand this aspect
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