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Children who have methylation issues like those with a folate or B12 deficiency secondary to malabsorption, autism, Down syndrome, autoimmune disease like PANS/PANDAS and others are at increased risk for histamine intolerance

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Journal of Biological Chemistry, 289(28), 1950819518

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This "double deficiency" can leave cells vulnerable

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However, factors such as dehydration can potentially affect the accuracy of these tests, leading to BAC readings that may not accurately reflect a person's level of impairment

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