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It is used in research on energy metabolism and, in certain specific clinical contexts, under professional indication and supervision
Cagrilintide lasts days
This complex interacts with RNA polymerase II (RNAP II) and stimulates the initiation and elongation of transcription
Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury
One trial suggests it may help reduce weight in overweight people with diabetes when used as an add on to the anti-obesity drug orlistat [2]
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