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In addition to being a therapeutic target, oxidative stress has been shown to decrease the GSH:GSSG ratio which has proven useful as a clinically accessible, pharmacodynamic biomarker of immune redox tone for conditions such as malignancy (Zitka et al., 2012)
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However, when combined with insulin or sulphonylureas, dose adjustments of these other medicines may be necessary to prevent hypoglycaemia
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