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It's important to note that semaglutide is not recommended during pregnancy or breastfeeding, and women of childbearing potential should use effective contraception

Este frmaco acta como un agonista dual de los receptores GIP (polipptido insulinotrpico dependiente de glucosa) y GLP-1 (pptido similar al glucagn-1), produciendo efectos metablicos complementarios

Starting with a low dosesuch as 0.25 mggenerally produces milder and slower-onset symptoms compared to higher starting doses

This effect was then shown to be mimicked by GLP-1 that acted on the same receptor (94)

Kendall DM, Sutherland DE, Najarian JS, Goetz FC, Robertson RP