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When ligands (such as IS, IAA, and kynurenine) bind to AhR, AhR is released from the chaperone protein complex and translocates to the nucleus, where it heterodimerizes with aryl hydrocarbon receptor nuclear translocator (ARNT), then binds to xenobiotic response elements (XRE) or dioxin response elements (DRE) to induce downstream target gene transcription (120)
c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma
Serine proteinase inhibitors from nematodes and the arms race between host and pathogen
Fatigue Fatigue is the number one die-off symptom we hear from our clients
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