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Preclinical research suggests NNMT inhibition may affect fat cell metabolism, insulin sensitivity, body weight, and energy expenditure in animal or cell models

The most commonly reported adverse events were mild-to-moderate headache and gastrointestinal effects including flatulence and mild diarrhea

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Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence similarity to hormone-sensitive lipase

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