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Moreover, male mice allowed to the research group to adhere to 3 rs principles for animal studies, because the hyperglycemia threshold of 200 mg/dl fixed for the experimental plan and to proceed with semaglutide treatment was reached faster and more consistently (1011 weeks) with a less number of animals compared to female mice, which usually are protected against HFD-induced metabolic alterations [45], dilating time to achieve hyperglycemia condition
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214 Microglia in the SN of PD patients showed a higher proportion of amoeboid morphology, which is indicative of a reactive state
When preparing your IM injection, draw up the prescribed amount (for example, 1 mL) into the syringe
Sex- and gender-based pharmacological response to drugs
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