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Description

Life Sci, 2016

The resultant motor and non-motor symptoms include postural reflex deficits, bradykinesia, muscular rigidity, gait disturbances, and resting tremor (144, 145)

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This analysis was divided into two cohorts

While the precise pathogenesis remains elusive, current hypotheses implicate abnormal aggregation of -synuclein, mitochondrial dysfunction, calcium dyshomeostasis, oxidative stress, and neuroinflammation (146)