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If the solution remains cloudy or has visible particles after 30 minutes of gentle rolling, something may be wrong with the peptide
The experimental nature of these treatments necessitates thorough discussion of risks, benefits, and alternatives with patients, along with comprehensive informed consent procedures
2012;22:e1-7
B., Kiser, W
Excipient studies on lyophilized rhGH show that sugar and polyol stabilizers (mannitol, sucrose, trehalose) protect the protein's secondary structure and limit aggregation in the dry state by satisfying water-binding sites and stabilizing the amorphous matrix around the protein (Costantino et al., 1998)
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