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Nature 609 , 829834 (2022)
Targeted fat reduction through Semaglutide weight loss helps preserve lean tissue while shedding fat stores
HDAC7-mediated deacetylation stabilizes PSAT1, thereby affecting serine metabolism and the sensitivity of lung adenocarcinoma (LUAD) cells to the chemotherapeutic agent cisplatin (111)
Trial STEP 2 (Davies et al., Lancet 2021) Design Phase 3 / 68 weeks Population 1,210 adults with T2D and overweight or obesity Key result -9.6% body weight (2.4 mg) vs -3.4% placebo
These not only aid in the stability of the liposomes but can also offer additional metabolic benefits
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