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Researchers who abandon protocols after 3 to 5 days because they do not "feel anything" are not giving the compound adequate time to work
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In both in vivo patient-derived xenograft models and in vitro patient-derived organoid models, high-MCU PDAC show increased sensitivity to SLC7A11 inhibition compared to low-MCU tumors, 163 suggesting that MCU-mediated ferroptosis could serve as a therapeutic strategy to prevent PDAC tumor metastasis
This means the entire notion of a "human side-effect profile" for BPC-157 rests on extrapolation from animals plus uncontrolled anecdote
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