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According to a study conducted in Wuhan, China, more than 55% of previously disorders COVID-19 patients continued to report symptoms two years after discharge (9)
We recently identified the FOXO4 p53 axis as pivotal in maintaining the viability of senescent cells, and that senescent cells can be targeted selectively with the senolytic peptide FOXO4-DRI
It acts as a mitochondrial protective agent, stabilizing mitochondrial structure, enhancing oxidative phosphorylation, reducing production of reactive oxygen species (ROS), and mitigating cellular damage in diverse models of mitochondrial dysfunction
doi:10.2337/dc23-1420
They also urge caution for people with diabetes who are using GLP-1 drugs off-label or for weight loss, especially when experiencing side effects that might lead them to consider dialing back their insulin dosage
