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We observed that GLP-1RAs were associated with reduced levels of BMI (OR 0.70 [95% CI 0.490.99], P = 4.50 10 2 ), current tobacco smoking (OR 0.77 [95%CI 0.670.89], P = 2.98 10 4 ), and alcohol consumption (OR 0.72 [95% CI 0.550.95], P = 2.07 10 2 )
Early phase 2 data showed average weight loss of approximately 24 percent at 48 weeks, with the STEP UP trial demonstrating 20.7 percent average weight reduction with the higher dose formulation at 72 weeks
Brandt, S
Your provider must review these safety parameters before initiating any combination
The switching from tirzepatide to semaglutide guide covers the dosing transition protocol
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