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Based on animal reproduction studies showing fetal harm at clinically relevant exposures, the FDA recommends that semaglutide should be discontinued at least 2 months before a planned pregnancy due to its long washout period (approximately 5 weeks after the last dose)
Please talk to a healthcare provider if you experience fatigue for an extended period
Individual results vary based on clinical factors, adherence, and lifestyle.
And that is also why stopping them commonly allows those signals to return
Interface Focus, 7 (6), 20170030
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