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The study team was led by Prof Michele Tagliati of the Cedar Sinai medical centre

Dopamine and conditioned reinforcement: I

The SURMOUNT trials demonstrated tirzepatide at 15 mg achieving 15% to 21% body weight loss by week 72, about 17 months

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3, significant superiority in primary CV outcome was observed in three CVOTs using GLP-1 RAs (liraglutide OD in LEADER [56], dulaglutide OW in REWIND [36], and semaglutide OW in SUSTAIN 6 [non-inferiority and superiority were demonstrated in SUSTAIN 6 and pre-specified sensitivity analyses, respectively] [37])