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Hypoglycemia, although rare with Semaglutide monotherapy, may occur when used in combination with other glucose-lowering medications, particularly insulin or sulfonylureas
Elevated risks of coronary artery disease and heart failure persisted in those who discontinued early, while risks of acute coronary syndromes, stroke, and mortality were similar between groups
The exact mechanism of action for topiramate with weight loss is not known, but it is thought to decrease appetite and enhance satiety
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