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The community's 250 mcg twice weekly (0.5 mg/week, ~70 mcg/day equivalent) is conservative compared to clinical data (FDA implant ~14 mg/week), and the newer ~50 mcg/day loading dose is lower still
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Furthermore, improvements in global cognitive function and memory performance in Parkinsons disease patients occurred only after combined intervention and remained stable during follow-up (Manenti et al., 2016)
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