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The FDA clinical studies were focused around correction of moderate to severe facial wrinkles and folds, such as nasolabial folds in adults over the age of 21
Data analysed by one-way ANOVA, multiple comparison, Bonferroni post hoc test ( e , f , k and l ) and two-way repeated measures ANOVA to assess main effects of treatment ( b , d , h - j , n and p )
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