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They might come with the wrong amount of active ingredients, unusual dosing instructions, or unsafe ingredients
Jayne Hornung, chief clinical officer at Managed Markets Insight and Technology, suggests initial pricing of oral GLP-1s for weight loss could be reminiscent of the early days of anti-CGRP medications for migraines when the first oral CGRP came to market in 2019, the pricing still remained high
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Glomerular filtration rate (GFR) is the most important measure of kidney function
The authors also postulate that, besides the demonstrated pro-tumorigenic role of CAFs, previous attempts at targeting fibroblasts to treat cancer may have been unsuccessful because they mainly targeted the myCAF subpopulation while leaving other subsets unaffected
