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Prolonged daily use increases the risk of the onset of symptoms as rash, hives, itching, swelling, hoarseness, difficulty in breathing and also of more severe complications as stomach bleeding, kidney or liver damage, thrombocytopenia, leukopenia, anemia, agranulocytosis, epidermal necrolisys, multiform erythema, Steven-Jhonsons syndrome

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[14] However, semaglutide offers distinct advantages in specific clinical contexts