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All samples were kept at 5C in the auto-sampler tray for the duration of the analysis
Thus, even if systemic changes in GLP- 1 levels might not be readily detectable, altered paracrine signaling of GLP-1 could have profound effects on enterochromaffin cells (as mentioned above) (5153), intraepithelial lymphocytes (29) and afferent neurons, in turn impacting intestinal motility, mucosal immune responses and feeding behavior under inflammatory conditions (75)
The robust relationship between these two entities has been largely attributed to oxidative stress caused by hyperglycemia, although a few studies have failed to demonstrate a significant reduction in cardiovascular risk as a result of intense glycemic control [8486]
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Lin, Y., & Sun, Z
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