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Concordance with randomized trials was assessed using RCT-DUPLICATE predefined benchmarks to evaluate consistency in both direction and magnitude
SURMOUNT-5, published in the New England Journal of Medicine, directly compared the maximum tolerated doses of tirzepatide and semaglutide in the same patient population
Animal studies have not reported major toxicity, but the lack of comprehensive human data means risks are unknown467
M., Van Raalte, D
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