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The percentage of adults achieving an HbA1c of less than 7% at 32 weeks was 89.3% in the combination therapy group, 69% in the semaglutide group and 33.3% in the cagrilintide group

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Subgroup meta-analyses based on participants kidney function indicated that the salutary effects of SGLT2i on MACE, cardiovascular death or HHF, and a composite kidney outcome (substantial loss of kidney function, end-stage kidney disease or death due to kidney disease) do not significantly differ among subgroups based on eGFR [142, 252]

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