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For methylation and one-carbon metabolism research, methylcobalamin provides the biologically active form without requiring conversion steps

Research Disclaimer: Onyx Biolabs AOD-9604 is supplied strictly for in-vitro laboratory research and analytical purposes only

10.1016/j.molmet.2021.101296 69 MetzlerM.Legendre-GuilleminV.GanL.ChopraV.KwokA.McPhersonP

Results demonstrated that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo. Critically, the peptide produced no clinically significant alterations in IGF-1 levels, no glucose intolerance or insulin resistance, and no anti-AOD9604 antibodies in any participant

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