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The available human pharmacokinetic study involved only 18 healthy adults receiving a single high dose

doi: 10.1038/s43587-022-00337-2 391 YamadaM

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One reason for this is that the level of glutathione will fluctuate throughout the day from its lowest in the early morning to depletion from routine exposure to toxic substances (like alcohol), pathogens, cigarette smoke, car exhaust, drugs, certain foods, stress level, illness, and many similar factors, so repeated testing could be required to set a baseline

Ordonez et al., 2022)