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Introduction: Menopause, Hormones, and Oxidative Stress Menopause marks a significant transition in a womans life, typically between ages 45 and 55, as estrogen and progesterone levels decline

These conditions result in low IGF-I concentrations, and changes in IGF-I positively correlate with changes in lean body mass[369, 370], as well as reversal of acute catabolic states is associated with an increase in IGF-I levels[371, 372]

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Just recently, in 2024, publications covering this critical topic reached emergency room clinicians