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Zhao L, Zhang F, Ding X, et al
Triggers Several factors can make acne flare up or lead to breakouts, but the triggers can vary from person to person
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330 CAF-derived cytokines (e.g., IL-10, IL-6, CCL2) recruit and polarize macrophages into immunosuppressive M2-TAMs, which secrete TGF- and IL-10, suppressing cytotoxic T-cell responses and facilitating immune escape
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