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Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth
This is analogous to how 5-Amino-1MQ works in metabolic research-rather than adding a new signal, it removes a brake on an existing one (NNMT inhibition preserves NAD+
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M.AbdullahI.AhmadI.DufresneA.KargarzadehH
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