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D.O'SheaD.GunnI.BeakS
This connects directly to the audience data: 74% of GLP-1users say health is their primary food decision factor, and they strongly favor lower-calorie options
doi: 10.1111/apt.16166 201
(PubMed) Pons R, De Vivo DC
Additionally, the mucosal layer represents a major yet often overlooked barrier, acting as a dense, heterogenous matrix that traps and limits the diffusion of hydrophobic or charged peptides ( in vitro models, the limitations of which are not fully realized in the current formulation design space ( At the epithelial surface, paracellular transport is restrained by tight junctions, whereas transcellular uptake is constrained by efflux transporters and competition with endogenous substrates (Hamman et al., 2005)
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