DOI: 10.1016/j.cgh.2023.11.002 Hocking SL, Scott DA, Remedios ML, Horowitz M, Story DA, Greenfield JR, Boussioutas A, Devereaux B, Andrikopoulos S, Shaw JE, Olesnicky BL
Once-weekly injections of CT-388 led to placebo-adjusted weight loss of 22.5% at 48 weeks, without a weight loss plateau, according to Roches Tuesday announcement
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What are the FDA approval dates, indications, and dosing schedules for Wegovy (semaglutide) compared with Mounjaro (tirzepatide)?
It would be of interest to see if inhibition of USP14 by other means (IU1-47 treatment or USP14 depletion by siRNA) results in the activation of a similar pathway (e.g