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This suggests the pain relief observed in the trial is not purely a downstream consequence of losing weight but may involve a separate pathway
Combining them with NAD supplements can amplify the effects, but also potentially increase side effects like hot flashes, nausea, or headaches
Never combine GLP-1 receptor agonists
However, the care question becomes more complex because uncontrolled diabetes in pregnancy also creates real risks, so treatment should shift to pregnancy-appropriate diabetes management rather than simply leaving the condition untreated
Basic & clinical pharmacology & toxicology , 118 (1), 7076
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