Niacin is converted to NAD and NADP, two coenzymes involved in hundreds of redox (oxidationreduction) reactions, including those of glycolysis, the citric acid cycle, and fatty acid metabolism
This includes vegans and vegetarians, older adults, individuals with atrophic gastritis, pernicious anemia, gastrointestinal disorders, those who have had gastrointestinal surgery and people who take certain medications including, but not limited to, estrogen (HRT), and birth control pills
These actions help repair damaged tissues, reduce inflammation, and improve mobility
By attaching a palmitic acid chain, the molecule gains lipophilicity and crosses the stratum corneum more readily
Morris D, Khurasany M, Nguyen T, Kim J, Guilford F, Mehta R, et al