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These trials used Eli Lilly-manufactured tirzepatide
It is cash-pay only, does not apply to compounded tirzepatide, and usually requires a prescription through a provider connected to the program
Before starting, patients should undergo baseline bloodwork including oxidative stress markers, liver and kidney function, inflammatory cytokines, and ideally genetic assessment in glutathione metabolism pathways
Researchers later found that the drugs were very effective for weight loss, even in people who did not have diabetes
Genetic variants in GIPR pathways may also influence receptor sensitivity, though genetic predisposition does not determine treatment outcome alone
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