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Glutathione works through several mechanisms: The thiol group directly neutralizes free radicals It helps regenerate other essential antioxidants like vitamins C and E It binds with toxins to make them water-soluble for elimination It helps repair DNA damage through enzyme systems This molecular powerhouse balances production, consumption, and recycling to ensure our cells stay protected

The MFI was determined by flow cytometry (LSRFortessa TM

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Although the significance of ferroptosis in NAFLD and NASH remains unknown, malondialdehyde and 4-HNE, secondary lipid peroxidation products, have been widely considered indicators of oxidative stress in NASH patients (Loguercio et al., 2001)