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For example, patients who achieve even modest reductions in AHI scores often report improvements in energy levels, mood, and adherence to weight management programs

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(A 2022 clinical trial published in the New England Journal of Medicine found that roughly 80% of people taking Zepbound did.) Research and obesity medicine specialists have identified a few common patterns for when symptoms tend to flare up: Early on, especially during the first few weeks Within 48 hours of an injection After a dose increase Individual bouts of nausea, diarrhea and vomiting often pass within a few days, though constipation can stick around much longer