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Co-infusion of GLP-1 and GCG has been shown to reduce glucagon-induced hyperglycemia, lower blood glucose levels, suppress food intake, and enhance energy expenditure in both diabetic obese mice and healthy human volunteers [78]
It stimulates two key metabolic receptors: GLP-1, like Wegovy GIP, which further enhances insulin control and weight-loss effects Because of this dual mechanism, clinical studies show patients may lose 20% or more of their body weight, making Zepbound one of the most powerful options available today
Therefore, approval and written informed consent were waived by the ethics review board of the Ethical Committee of West China Second University Hospital of Sichuan University