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Tissues characterized by fast replicating cells also show reduced protein synthesis
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If one of these building blocks is lacking in sufficient amounts, the body's production can be limited
[76] [77] In a 72-week, phase IIIb open-label head-to-head trial of adults with obesity without diabetes, tirzepatide at the maximum tolerated dose produced greater mean weight loss than semaglutide and larger reductions in waist circumference, while gastrointestinal adverse events were the most common with both drugs
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