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TGF-, transforming growth factor-
This approach makes the process more motivating and less overwhelming
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Accordingly, mitochondrial fusion preserves the mitochondria for greater energy production during conditions of high metabolic activity, whereas fission facilitates the removal of damaged mitochondria via mitophagy (Scheibye-Knudsen et al., 2015)
This discrepancy may be attributed to several alternative, non-mutually exclusive hypotheses that must be considered with equal weight: (1) a misalignment between the drugs therapeutic window and the disease stage of the enrolled patients (the prevention hypothesis)
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