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The medication initiates this cascade
Counterintuitive at first glance glucagon raises glucose but its hepatic effect (lipolysis stimulation, lipid catabolism boost, steatosis reduction) outweighs the hyperglycemic signal when paired with a strong GLP-1 arm
Arachidonic acid in follicular fluid of pcos induces oxidative stress in a human ovarian granulosa tumor cell line (KGN) and upregulates GDF15 expression as a response
The results showed that LC significantly increased the expression of CYP11A1(cytochrome p450 11A1) (related to steroidogenesis) and TXNIP (thioredoxin interacting protein) (related to oxidative stress) and increased serum levels of follicle-stimulating hormone (FSH), reduced testosterone, luteinizing hormone (LH), glucose, insulin, and homeostasis model assessmentinsulin resistance
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