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This amplification of endogenous signaling rather than exogenous receptor activation is a mechanistically distinct approach to cognitive enhancement
Activated microglia drive the immune response to the inflammatory state releasing immune signaling molecules (cytokines, and chemokines), and inducing neuronal cell death ( These data underline the importance of optimal glycemic control and call for major pharmacological interventions to reduce the risk of cardiometabolic-related cognitive impairment
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