GLP-1R is expressed in the brainstem nucleus tractus solitarius, in the hypothalamic arcuate nucleus, in the vagus nerve, in the stomach, and in the heart
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When the body attempts to exert energy, the poisoned mitochondria simply cannot meet the demand, resulting in a severe, prolonged cellular energy crash that can leave a patient bedbound
Even losing 10-15 pounds can noticeably reduce symptoms by decreasing the repetitive trauma that prevents complete healing
The goals of treating xerostomia include identifying the possible cause(s), relieving discomfort, and preventing complications (e.g., dental caries and periodontal infections)