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Science, 2011
Glucuronidation also contributes to ochratoxin A detoxification, so UGT variants may have an overlapping impact across several mycotoxins.[ref] Related article: Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance Patulin and glutathione-dependent pathways: Patulin, a mycotoxin most commonly found in moldy apples and apple juice, binds to thiol groups in glutathione, depleting this key intracellular antioxidant and triggering oxidative stress and mitochondrial dysfunction
GHK-Cu is more polyvalent (healing + matrix + genome + hair) and more ancient in the literature
Importantly, expression levels of these genes have been used in numerous studies as sensitive indices for oxidative stress 8,19,20
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