Both share GI-dominant side effects, and head-to-head data showed broadly comparable tolerability
Shor, R
Glucagon-like peptide-1 receptor agonists as potential preventive and therapeutic agents in ischemic stroke 1 Department of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada 2 Department of Surgery, Division of Anatomy, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada 3 Department of Pharmacology and Toxicology, Temerty Faculty of Medicine, University of Toronto, Ontario, Canada 4 Banting and Best Diabetes Centre, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada Advanced Neurology 2026 , 5(2), 025150027 Received: 7 April 2025 | Revised: 13 July 2025 | Accepted: 22 July 2025 | Published online: 11 September 2025 Stroke remains a significant contributor to mortality and morbidity worldwide, imposing a significant socioeconomic burden and underscoring the urgent need for both preventative and therapeutic strategies

Dietary and Behavioral Modifications These changes should be implemented at the first sign of significant nausea or vomiting and maintained throughout therapy: Eat five to six very small meals per day rather than three standard ones
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