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FIGURE 13 In the aforementioned study by Hsieh and collaborators (Hsieh et al., 2017) that focused on the ischemic muscle model (achieved via removal of the femoral artery), the pro-angiogenic effects of BPC 157 are evident, given the increased expression, internalization of vascular endothelial growth factor receptor 2 (VEGFR2), and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)
Injection site reactions (redness, swelling, tenderness) are most common but typically resolve quickly
Information provided on this page is educational in nature and based on publicly available scientific literature describing biochemical and investigational research contexts
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This can result in nerve damage and other adverse effects, as has been recently reported
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