Upon infiltrating the liver, peripheral neutrophils from sAH patients are activated by the inflammatory milieu, including mediators such as TNF- and IL-1, leading to elevated expression of IL-8 [75]
However, recent literature has shown that TMAO not only passes through the FMO3 oxidation system of the liver but also through an oxidation pathway in the intestinal tract (9)
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Acromegaly: pathogenesis, diagnosis, and management