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Bacteriostatic vials allow multiple entries, but each entry must be done with a new sterile syringe/needle to avoid introducing pathogens

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This makes bacteriostatic water the standard choice for multi-dose vials, as it allows the solution to be stored and used for several weeks after the initial mixing

Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement

Animals, including humans, can convert cyanocobalamin to any one of the active vitamin B 12 compounds