Clinically, this modulation suggests vitamin A may enhance resistance to intracellular infections such as malaria without adverse pregnancy outcomes when given in low doses (Binka et al., 1995)
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These approaches have shown potential to increase therapeutic efficacy, reduce side effects, and target advanced, metastatic, and resistant ovarian cancers, though challenges like tumor environment and changing antigen expression require further refinement for clinical success (175, 176)
Preclinical studies indicate that microbiota modulation via diet or probiotics can reduce neuroinflammation and amyloid burden, with some animal models showing improved cognitive outcomes