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Role of intestinal permeability and probiotics in obesity and fatty liver disease The new concepts on the pathophysiology of obesity and associated metabolic diseases such as NAFLD and NASH, type 2 diabetes mellitus or cardiovascular diseases, stating that such pathologies are related to the intestinal barrier and the intestinal microbiota, derived predominantly from mouse studies

The safety profile is definitely very high

Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes

Weeks 4 to 8: Improvements either plateau or persist