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When introduced into subcutaneous tissue, this charge can create a temporary pH imbalance at the injection site

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Sonthalia, S., Daulatabad, D., & Sarkar, R

Stability of aminophylline in bacteriostatic water for parenteral-route administration [PMID: 1481803] Laboratory literature summary: Stability of aminophylline in bacteriostatic water for parenteral-route administration stored in plastic syringes at two temperatures

Common risks include unknown purity, inconsistent concentration, contamination, bad storage, sketchy supply chains, and misleading labels